Chinese Herbal Injection for Non-Small Cell Lung Cancer

The latest advancement in the treatment for lung cancer is an injection ‘Shenqi fuzheng’ made from Chinese medicinal herbs. The combined result of platinum-based chemotherapy and Shenqi fuzheng reduces toxicity associated with treatment of non-small cell lung cancer.

Lung cancer is the top cause of cancer-related deaths worldwide, of which non-small cell lung cancer accounts for about eighty five percent. Most cases at the time of diagnosis are already at the third an advanced inoperable stage of non-small cell lung cancer. For years, the standard and most widely used treatment for advanced non-small cell lung cancer has been the Platinum-based chemotherapy. The platinum-based chemotherapy has many advantages over its non-platinum-based counterparts which have been proved by various randomized clinical trials. However, as a side effect of the therapy, may seriously impact on the patient's survival chances and quality of life.

Shenqi Fuzheng is a newly formulated injection made from Chinese medicinal herbs. In the year 1999, the injection has been approved by the State Food and Drug Administration of the People's Republic of China primarily as an effective anti-tumor injection to be manufactured and marketed in China. Shenqi Fuzheng is manufactured from two kinds of Chinese medicinal herbs: Radix Astragali and Radix Codonopsis. Many published trials exist about the utilization of Shenqi Fuzheng Injection combined with platinum-based chemotherapy for treatment of advanced non-small cell lung cancer. However, there has been no systematic evaluation of its use outside China until now.

A recent systematic review explores the combined effect of the platinum-based chemotherapy and the use of ‘Shenqi fuzheng’, an injection made from Chinese medicinal herbs. Traditionally, in China, numerous Chinese medicinal herbs have been widely used in combination with the platinum-based chemotherapy for the treatment of advanced non-small cell lung cancer. The combining of the medicinal herbs with the therapy is found to significantly reduce the toxicity and improve the curative effect of the therapy.mFindings from earlier studies have also established that the combination of Chinese medicinal herbs with platinum-based chemotherapy for the treatment of advanced non-small cell lung cancer may possibly improve the survival rates, tumor response, and performance status, in addition to the reduced toxicity.

The results study point out significant inferences viz., increased efficacy and decreased toxicity. However, the study has its own share of limitations. Thus the findings demand further verification by using more high-quality experiments.

Reference:
Shenqi fuzheng, an injection concocted from Chinese medicinal herbs, combined with platinum-based chemotherapy for advanced non-small cell lung cancer: a systematic review- A study by Ju Dong, Shi-Yue Su, Min-Yan Wang, and Zhen Zhan, Institute of Basic Medical Science, China. For more information, please visit: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972256/?tool=pubmed

Disclaimer: This article is written by a non-medical professional.

Date: 
Sunday, January 30, 2011
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